Assistant Professor  Chien-Sheng Chen

Phone

Office: +886-2-29052475

Lab: +886-2-29053583

Fax: +886-2- 29023209

E-mail

092847@mail.fju.edu.tw

Link

 

Experiences and

honors:

B.S. (1994-1998) Dept. of Chem., National Tsing-Hua University, Prof. C.-C. Liaw

M.S. (1998-2000) Dept. of Chem., National Tsing-Hua University. Prof. S.-C. Hung

Research Assistant (2000-2001) Inst. of Biological Chemistry, Academia Sinica, Prof. S.-H Wu

Ph.D. (2001-2007) Dept. of Chem., National Taiwan University, Prof. J.-M. Fang

Visiting Ph.D. student, 2005, Institute for Biological Chemistry, NRC/CNRC, Ottawa, Canada, Prof. Wei ZouMilitary Serve (2007-2008)

 

Postdoctoral Fellow (2008-2011) Inst. of Biological Chemistry, Academia Sinica, Prof. S.-H Wu

Postdoctoral Fellow (2011-2012) Dept. of Chemistry, University of California, Davis. USA, Prof. Jacquelyn Gervay-Hague

Assistant Professor (2013.02-Now), Dept. of Chemistry, Fu Jen University

 

Honor:

1.     Oral Presentation in Sialoglyco 2010, Potsdam, Germany. (Functional Support by Foundation for the Advancement of Outstanding Scholarship)

2.     Young Scientist Talk and Travel Award, 3rd APNMR, 2009 Biannual Asia-Pacific NMR Symposium, Jeju, Korea. (Functional Support by the APNMR Conference)

3.     Award of Outstanding for the 2010 Taiwan Magnetic Resonance Society Symposium.

4.     Poster Award 2006 in Chem. Dept. of NTU. (Provided by TaiGen Biotechnology)

Field

Researching Area: Bioorganic Chemistry, Detection of Glycoprotein, Acoustic Composite

Research Interests

Classical acoustics uses electric energy to drive a coil, which drives the sound film and produces sound wave. The current production of nanocomposite sound film in this group is applied to the manufacture of loudspeaker and headphone. The selected nanomaterials, including graphene, carbon nanotubes, and planar porphyrins, were applied to modify paper-based membrane, Mylar membrane, and biofilm.

Recent Publications

26. Chen, C.-S.*, Li, H.-Z.; Wu, J.-J., C. B. Speaker Diaphragm Structure. United States Patent US 2020/0077195 A1.

25. Xu , L.; Luo, C.-H.; Chen, C.-S.*. Halogenation and anomerization of glycopyranoside by TESH/bromine and BHQ/bromine. J. Chin. Chem. Soc., 2020, 25, 1-7.

24. Li, H.-Z.; Wu, J.-J.; Lee, W.-J.; Chen, C.-S.* Improving the High-Frequency Response of PEI-based Earphone with Sodium Copper Chlorophyllin. Molecules, 2020, 25, 219-228.

23. Chen, C.-S.*; Xu, L.; Lee, W.-J. Electrochemical lactonization of trisialic acid. J. Chin. Chem. Soc. 2018, 1245-1250.

22. 陳建盛, 李濠志, 李維仁, 音膜結構. 中華民國發明專利第I683583, 中國大陸發明專利證書號第4206234.

21. Chen, C.-S.*; Lee, W.-J. Study of the Enzymatic Activity of Arthrobacter ureafaciens Neuraminidase by Isothermal Titration Calorimetry. J. Chin. Chem. Soc. 2018, 271–275.

20. Lai, Y.-C.; Luo, C.-H.; Chou, H.-C.; Yang, C.-J.; Lu, L. Chen, C.-S.* Conversion of b-glycopyranoside to a-glycopyranoside by photo-activated radical reaction. Tetrahedron Lett. 2016, 57, 2474–2477.

 

博士後研究

19. Tsai, C.-C.; Yang, F.-L.; Huang, Z.-H.; Chen, C.-S.; Yang, Y.-L.; Hua, K.-F. Li, J.; Chen, S.-T. Wu, S.-H. Oligosaccharide and Peptidoglycan of Ganoderma lucidum Activate the Immune Response in Human Mononuclear Cells. J. Agric. Food Chem. 201260, 2830−2837.

18. Chen, C.-S.*; Yu, Y.-P.; Cheng, M.-C.; Zou, W.; Fang, J.-M.; Wu, S.-H.* Evaluation of the Regioselective Delactonization of Tri-Sialic Acid Lactone by In-Solution Molecular Dynamics Simulation. Carbohydr. Res. 2012354, 87-93. (*Corresponding Author)

17. Liaw, C.-C.; Liao, W.-Y.; Chen, C.-S.; Wu, Y.-C.; Jao, S.-C. Shen, C.-N.; Wu, S.-H., Calcium- chelating capability of acetogenins modulates their cytotoxicity. Angew. Chem. Int. Ed. 201150, 7885-7891.

16. Eckert, T.; Lu, C.-P; Chen, C.-S.; Wu, S.-H.; Gervay-Hague J.*, NMR studies of the reversible and regioselective lactonization of α-2,8-linked trisialic acid in aqueous acid. Tetrahedron Lett. 201152, 2250-2253.

15. Liao, J.-H.Chen, C.-S.; Lin, I.-L.; Huang, Y.-H.; Tsai, M.-H.; Huang, F.-Y.; Wu, T.-H. Hu, C.-C. Wu, S.-H., Ditopic Complexation of Selenite Anion or Calcium Cation by Pirenoxine: Implications for Cataract Prevention. Inorg. Chem. 201150, 365-377. ( Equal contribution to this work, ACS selected paper)

14. Yu, Y.-P.; Wu, A.-T.; Zou, W.; Chen, C.-S.*; Wu, S.-H.*, Recognition between a divalent sialyl molecule and wheat germ agglutinin. Tetrahedron Lett. 200950, 6130-6132. (*Corresponding Author)

13. Liao, J.-H.; Chen, C.-S.; Maher, T.-J.; Liu, C.-Y.; Lin, M.-H.; Wu, T.-H.; Wu, S.-H., Astaxanthin interacts with selenite and attenuates selenite-induced cataractogenesis. Chem. Res. Toxicol. 200922, 518-525.

12. Chen, C.-S.*; Yu, Y.-P.; Lin, B.-C.; Gervay-Hague, J.; Fang, J.-M.; Hsu, C.-P.; Wu, S. H.*, The observation of the C–H ··· Osp3 hydrogen bond in trisialic acid lactone and its implications for cooperative lactonization. Eur. J. Org. Chem. 2009, 3351-3356. (*Corresponding Author and Selected as Cover Picture)

 

博士班

11. Chen, C.-S.; Yu, Y.-P.; Hsu, C.-H.; Wu, Y.-T.; Zou, W.; Fang, J.-M.; Wu, S.-H., Conformation of trisialic acid lactone: NMR spectroscopic analysis and molecular dynamics simulation. Eur. J. Org. Chem. 2007, 3648-3654.

10. Chen, C.-S.; Wu, S.-H.; Wu, Y.-Y.; Fang, J.-M.; Wu, T.-H., Properties of astaxanthin/Ca2+ complex formation in the deceleration of cis/trans isomerization. Org. Lett. 20079, 2985-2988.

9. Shao, H.; Ekthawatchai, S.; Chen, C.-S.; Wu, S.-H.; Zou, W., 1,2-migration of 2'-oxoalkyl group and concomitant synthesis of 2-C-branched O-, S-glycosides and glycosyl azides via 1,2-cyclopropanated sugars. J. Org. Chem. 200570, 4726-4734.

8. Yang, F.-L.; Lu, C.-P.; Chen, C.-S.; Chen, M.-Y.; Hsiao, H.-L.; Su, Y.; Tsay, S.-S.; Zou, W.; Wu, S.-H., Structural determination of the polar glycoglycerolipids from thermophilic bacteria Meiothermus taiwanensis. Eur. J. Biochem. 2004271, 4545-4551.

7. Lu, T.-L.; Chen, C.-S.; Yang, F.-L.; Fang, J.-M.; Chen, M.-Y.; Tsay, S.-S.; Li, J.; Zou, W.; Wu, S.-H., Structure of a major glycolipid from Thermus oshimai NTU-063. Carbohydr. Res. 2004339, 2593-2598.

6. Ren, C.-T.; Chen, C.-S.; Yu, Y.-P.; Tsai, Y.-F.; Lin, P.-Y.; Chen, Y.-J.; Zou, W.; Wu, S.-H., Synthesis of alpha-(2-->5)Neu5Gc oligomers. Chem. Eur. J. 20039, 1085-1095.

5. Kuo, L.-J.; Liao, J.-H.; Chen, C.-T.; Huang, C.-H.; Chen, C.-S.; Fang, J.-M., Two-arm ferrocene amide compounds: synclinal conformations for selective sensing of dihydrogen phosphate ion. Org. Lett. 20035, 1821-1824.

4. Ren, C.-T.; Chen, C.-S.; Wu, S.-H., Synthesis of a sialic acid dimer derivative, 2'alpha-O-benzyl Neu5Ac-alph-(2-->5)Neu5Gc. J. Org. Chem. 200267, 1376-1379.

 

碩士班

3. Lee, J.-C.; Chang, S.-W.; Liao, C.-C.; Chi, F.-C.; Chen, C.-S.; Wen, Y.-S.; Wang, C.-C.; Kulkarni, S.-S.; Puranik, R.; Liu, Y.-H.; Hung, S.-C., From D-glucose to biologically potent L-hexose derivatives: synthesis of alpha-L-iduronidase fluorogenic detector and the disaccharide moieties of bleomycin A2 and heparan sulfate. Chem. Eur. J. 200410, 399-415.

2. Hung, S.-C.; Wang, C.-C.; Chang, S.-W.; Chen, C.-S., 1,6-Anhydro-b-L-hexopyranoses as Valuable Building Blocks Toward the Synthesis of L-Gulosamine and L-Altrose Derivatives. Tetrahedron Lett. 200142, 1321-1324.

1. Hung, S.-C.; Chen, C.-S., Efficient Synthesis of 1,2,3,4,6-Penta-O-acetyl-L-idopyranose. J. Chin. Chem. Soc. 200047, 1257-1262.

 

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