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李慧玲 教授 |
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通訊處 |
辦公室電話︰(02)2905-3573 實驗室電話：(02)2905-2479 |
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E-mail |
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學經歷 |
高雄醫學院 化學系學士 (1995) 輔仁大學化學研究所分析化學博士 (2004) 國家衛生研究院 環境衛生與職業醫學組 博士後研究 (2008) 輔仁大學化學系助理教授 (2009~) 輔仁大學化學系副教授(2012.8) 輔仁大學化學系教授 (2017.8) 輔仁大學環安衛中心主任 (2018.8~2020.7) 輔仁大學化學系系主任(2020.8~) |
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榮譽獎勵 |
1. 1040312 傑出研究獎 2. 1041111 班級導師經營獎 3. 1050107教學成果獎 4. 103年榮獲科技部優秀人才獎勵 5. 104年榮獲科技部優秀人才獎勵 6. 105 年榮獲科技部優秀人才獎勵 7. 106年榮獲科技部優秀人才獎勵 8. 107年榮獲科技部優秀人才獎勵 9. 108年榮獲科技部優秀人才獎勵 10. 1090211傑出研究獎 (107 學年) 11. 輔仁大學「焯炤講座」(109學年度∼112學年度) |
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學術專長 |
生化與環境分析化學、電化學及質譜分析 |
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研究領域 |
1. 以高效能液相層析儀串聯質譜分析 (HPLC-MS/MS) 來研究環境污染物 (如砷、二手煙、奈米材料、揮發性有機氣體、PM2.5和PAHs)以及對人體健康危害的生物性指標物如DNA 氧化性傷害研究之8-OHdG (8-oxo-7,8-dihydro-2’-deoxyguanosine)、DNA 甲基化(Global methylation)、脂質過氧化(Lipid peroxidation) 之8-iso-prostaglandin F2α、香煙致癌物NNK 的代謝物種和揮發性有機氣體代謝物種分析。 2. 串聯式四極柱質譜儀與飛行時間質譜儀 (LC-Q-TOF) 研究暴露質體學(Exposomics) 以動物模式和人體暴露於環境污染物下，進行 全面性的代謝輪廓譜分析(Metabolite profiling) 和代謝物標靶分析(Metabolite target
analysis) 找出新穎的生物性指標物如胺基酸 (Amino acids)、色胺酸代謝物(Tryptophan
metabolites)、花生四烯酸代謝物(Arachidonic acid metabolites) 以及全氟碳化合物系列 (Perfluoroalkyl
substances, PFAS) 等。 3. 開發新穎材料應用於樣品前處理領域，如金屬有機骨架化合物(Metal–organic frameworks, MOFs)、磁性奈米材料等。 |
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代表著作 |
1.
“Global
DNA methylation mediates the association between urine ono-2-ethylhexyl phthalate
and serum apoptotic microparticles in a young Taiwanese population” Chien-Yu
Lin, Ching-Way Chen, Hui-Ling Lee, Charlene Wu, Chikang
Wang, Fung-Chang Sung, Ta-Chen Su*, Science of the Total Environment,
2022, 808, 152054 (SCI, impact factor: 7.967, Ranking (Environmental
Sciences): 25/274 =9.12 %). Times cited: 0 2.
“Association
between the total plasma isomers of per- and polyfluoroalkyl substances and
erythrograms in young and middle-aged Taiwanese populations”, Chien-Yu Lin, Hui-Ling Lee, Chikang Wang,
Fung-Chang Sung, Ta-Chen Su “Ecotoxicology and Environmental safety 227
(2021) 112902, (SCI, impact factor: 6.291, Ranking (Environmental Science):
40/274 =14.59 %, 5-Year IF: 6.23) Times cited: 0 3.
Polydopamine
and silica nanoparticles magnetic solid phase extraction coupled with liquid
chromatography-tandem mass spectrometry to determine phenolic acids and
flavonoids in fruit wine”, Hui-Ling
Lee*, Chih-Yuan Kang, Yen-Jung Kuo, Shan-Ni Tseng “Journal of Food and
Drug Analysis, 29 (2021) 391-401,
https://doi.org/10.38212/2224-6614.3359,
SCI, impact factor: 6.079, Ranking (FOOD SCIENCE & TECHNOLOGY): 12/144
=8.33 %, 5-Year IF: 5.979) Times cited: 0 4.
“Lipid
peroxidation metabolites associated with biomarkers of inflammation and
oxidation stress in workers handling carbon nanotubes and metal oxide
nanoparticles” Wei-Te Wu, Wei-Ting Jung,
Hui-Ling Lee* Nanotoxicology, 15 (2021) 577-587, DOI:
10.1080/17435390.2021.1879303, SCI, impact factor: 5.913, Ranking
(Toxicology): 10/93 =10.75 %, 5-Year IF: 6.212) Times cited: 0 5.
“Relationships
among cigarette smoking, urinary biomarkers, and urothelial carcinoma risk: a
case-control study” Chi-Jung Chung, Hui-Tsung Hsu, Chao-Hsiang Chang,
Sheng-Wei Li, Chiu-Shong Liu, Mu-Chi Chung, Guo-Wei Wu, Wei-Ting Jung,
Yen-Jung Kuo, Hui-Ling Lee*,
Environmental Science and Pollution Research 47 (2020) 43177-43185, DOI:
10.1007/s11356-020-10196-2 SCI, impact factor: 4.223, Ranking (Environmental
Science): 91/274 =33.21%, 5-Year IF: 4.306) Times cited: 0 6.
“Urinary heavy metals, DNA
methylation, and subclinical atherosclerosiss” Chien-Yu Lin, Hui-Ling Lee,
Yi-Ting Hwang, Po-Chin Huang, Chikang Wang, Fung-Chang Sung, Charlene Wu,
Ta-Chen Su*,
Ecotoxicology and Environmental Safety 204 (2020) 111039,
https://doi.org/10.1016/j.ecoenv.2020.111039 (SCI, impact factor: 4.872,
Ranking (Environmental Science):
44/265 =16.60 %, 5-Year IF: 4.966) Times cited: 0 7.
“Determination of sunset yellow and tartrazine in drinks using
screen-printed carbon electrodes modified with reduced graphene oxide and
NiBTC frameworks” Jen-Han
Wu, Hui-Ling Lee.* Microchemical Journal 158 (2020) 105133,
https://doi.org/10.1016/j.microc.2020.105133 (SCI, impact factor: 3.206,
Ranking (Chemistry, Analytical): 20/84 =23.80 %, 5-Year IF: 2.993) Times
cited: 0 8.
“The association between urine di-(2-ethylhexyl) phthalate metabolites,
global DNA methylation, and subclinical atherosclerosis in a young Taiwanese”
Chien-Yu Lin, Hui-Ling Lee, Yi-Ting Hwang, Chikang Wang, Chia-Jung
Hsieh, Charlene Wu, Fung-Chang Sung, Ta-Chen Sui* Environmental Pollution 265 (2020)
114912, populationhttps://doi.org/10.1016/j.envpol.2020.114912 (SCI, impact
factor: 5.741, Ranking (Environmental Science): 40/242 = 16.53 %, 5-Year IF:
5.291) Times cited: 0 9. “The association between urinary levels of 1,3-butadiene metabolites, cardiovascular risk factors, microparticles, and oxidative stress products in adolescents and young adults” Chien-Yu Lin, Hui-Ling Lee, Wei-Ting Jung, Fung-Chang Sung, Ta-Chen Su.∗ Journal of Hazardous Materials, 2020, 396, 122745. DOI: 10.1016/j.jhazmat.2020.122745 (SCI, impact factor: 6.065, Ranking (Environmental Science): 13/242 = 5.37 %, 5-Year IF: 6.513) Times cited:0 10.
‘Multiwalled carbon nanotubes /reduced graphene
oxide nanocomposite electrode for electroanalytical determination of
bisphenol A, 8-hydroxy-2’-deoxyguanosine and hydroquinone in urine”
Jhih-Sheng Chen, Yi Li, Meng-Jhe Yu, Hui-Ling Lee*, International Journal of
Environmental Analytical Chemistry,
2020, 100, 774-788, July 15 2019 DOI:
10.1080/03067319.2019.1640874 (通訊作者, SCI, impact factor: 1.267 Ranking (Chemistry
Analytical)): 64/84 =76.16 % , 5-Year IF: 1.324). Times
cited: 0 11.
“The association between total serum isomers of
per- and polyfluoroalkyl substances, lipid profiles, and the DNA
oxidative/nitrative stress biomarkers in middle-aged Taiwanese adults” Chien-Yu Lina, Hui-Ling Lee,
Yi-Ting Hwang, Ta-Chen Su.∗ Environmental Research 182 (2020) 109064.
DOI: 10.1016/j.envres.2019.109064
(SCI, impact factor: 5.026, Ranking (Environmental Science): 33/251 = 13.14
%, 5-Year IF: 5.051) Times cited: 0 12.
Longitudinal follow-up of health effects among
workers handling engineered nanomaterials: a panel study” Wei-Te Wu,* Lih-Ann
Li, Tsui-Chun Tsou, Shu-Li Wang, Hui-Ling Lee, Tung-Sheng Shih and
Saou-Hsing Liou, Environmental Health (2019)
18:107https://doi.org/10.1186/s12940-019-0542-y (SCI, impact factor: 5.714,
Ranking (Environmental Science): 48/251 = 19.12 %, 5-Year IF: 5.075) Times
cited: 0 13.
SEPT14 mutations and teratozoospermia: genetic
effects on sperm head morphology and DNA integrity” Ya-Yun Wang, Tsung-Hsuan
Lai, Mei-Feng Chen, Hui-Ling Lee,
Pao-Lin Kuo, Ying-Hung Lin*
J
Clin Med. 2019 Aug 23;8(9). pii: E1297. doi:
10.3390/jcm8091297 14.
Measurement of urinary arsenic profiles and DNA
hypomethylation in a case-control study of urothelial carcinoma”, Chi‑Jung Chung, Hui‑Ling Lee,
Chao‑Hsiang Chang, Han Chang, Chiu‑Shong Liu, Wei‑Ting Jung, Huei‑Ju Liu,
Saou‑Hsing Liou, Mu‑Chi Chung, Yu‑Mei Hsueh, Archives of Toxicology., July 30, 2019 (SCI,
impact factor: 5.741, Ranking (Toxicology): 7/93 = 7 %, 5-Year IF: 6.044). https://doi.org/10.1007/s00204-019-02500-y 15.
Investigating
the association between urinary levels of acrylonitrile metabolite
N-acetyl-S-(2-cyanoethyl)-L-cysteine and the oxidative stress product
8-hydroxydeoxyguanosine in adolescents and young adults” Chien-Yu Lin,
Hui-Ling Lee, Fung-Chang Sung , Ta-Chen Su. Environmental Pollution 2018,
239, 493-498 (SCI, impact factor:
5.099, Ranking (Environmental Science): 20/229 = 8.73 %, 5-Year IF: 5.552) 16.
“Rapid
analysis of traditional Chinese medicine Pinellia ternata by microchip
electrophoresis with electrochemical detection” Tsung-Ting Shih, Hui-Ling
Lee*, Show-Chuen Chen,. Chih-Yuan Kang, Ren-Shang Shen, Yi-An Su, J Sep Sci
2018, 41, 740–746. DOI: 10.1002/jssc.201700901(通訊作者, SCI,
impact factor: 2.557, Ranking (Chemistry Analytical)): 30/76 =39.47 % ,
5-Year IF: 2.457). 17.
“Targeted lipidomics profiling of acute
arsenic exposure in mice serum by on-line solid-phase extraction
stable-isotope dilution liquid chromatography–tandem mass spectrometry”
Chao-Yu Chen, Pinpin Lin, Ming-Hsien Tsai, Hui-Ling Lee*, Archives
of Toxicology., 2017, x, xxx DOI 10.1007/s00204-017-1937-6 (通訊作者, SCI, impact factor: 6.637, Ranking (Toxicology): 5/90 = 5.5 % ,
5-Year IF: 6.637). Times cited: 0. 18.
“Involvement of the
cytokine–IDO1–AhR loop in zinc oxide nanoparticle-induced acute pulmonary inflammation” Chia-Chi Ho, Hui-Ling Lee, Chao-Yu Chen, Yueh-Hsia Luo, Ming-Hsien Tsai,
Hui-Ti Tsai & Pinpin Lin∗,
nanotoxicology, 2017, 11, No 3, 360–370 http://dx.doi.org/10.1080/17435390.2017.1306129, (SCI, impact factor: 7.913, Ranking (Toxicology): 4/90 = 4.44 % , 5-Year IF:
7.913). Times cited: 0 19. “Positive association between urinary concentration of phthalate
metabolites and oxidation of DNA and lipid in adolescents and young adults”, Chien-Yu Lin, Pau-Chung Chen, Chia-Jung
Hsieh, Chao-Yu Chen, Anren Hu, Fung-Chang Sung, Hui-Ling Lee∗, Ta-Chen Su∗,Scientific Reports , 2017,7:44318 / DOI:
10.1038/srep44318 (SCI, impact factor: 5.228, Ranking (Multidisciplinary
sciences): 7/63 = 11.1 %, 5-Year IF: 5.525).
Times cited: 0 20. “Global DNA methylation and oxidative stress biomarkers in workers
exposed to metal oxide nanoparticles”, Saou-Hsing Liou, Wei-Te Wu, Hui-Yi
Liao, Chao-Yu Chen, Cheng-Yen Tsai,Wei-Ting Jung, Hui-Ling Lee∗, Journal
of Hazardous Materials,
2017, 331, 329– 335 (SCI, impact
factor: 4.836, Ranking (Environmental Science): 19/225 =
8.44 %,
5-Year IF: 5.641) 21. “Relationships among DNA hypomethylation, Cd, and Pb exposure and risk
of cigarette smoking-related urothelial carcinoma”, Chi-Jung Chung,
Chao-Hsiang Chang, Saou-Hsing Lioue, Chiu-Shong Liu, Huei-Ju Liue, Li-Ching
Hsua, Jhih-Sheng Cheng, Hui-Ling Lee*, Toxicology and Applied Pharmacology, Volume 316, 1 February
2017, Pages 107–113 (SCI, impact factor: 3.847,
Ranking (Toxicology):
12/89 = 13.48 %, 5-Year IF:
4.010). Times cited: 0 22. “Simultaneous, rapid, and sensitive
quantification of 8-hydroxy-2′-deoxyguanosine and cotinine in human urine by
on-line solid-phase extraction LC-MS/MS: correlation with tobacco exposure
biomarkers NNAL”, Chao-Yu Chen,Yu-Ting Jhou, Hui-Ling Lee*,
Yu-Wen Lin, Analytical and Bioanalytical Chemistry, 2016, 408, 6295–6306. (通訊作者) (SCI, impact factor: 3.125, Ranking
(Chemistry, Analytical): 15/75 = 20 %, 5-Year IF: 3.32). Times cited: 0. 23.
“Changes of serum amino acid profiles by an
epidermal growth factor receptor mutation and benzo[a]pyrene in mouse lung
tumorigenesis”, Pinpin Lin,
Yi-Rong Chen, Chao-Yu Chen, Ya-Ting Chang, Jhih-Sheng Chen, Ming-Hsien
Tsai, Cheng-Chin Kuo, Hui-Ling Lee*, Toxicology Research.,
2016, 5, 1182-1192 (通訊作者, SCI, impact factor: 2.161, Ranking (Toxicology): 51/89 = 57.3 % ,
5-Year IF: 2.752). Times cited: 0.
24.
“Increased levels of oxidative stress
biomarkers in metal oxides nanomaterial-handling workers”, Saou-Hsing Liou,
Yu-Cheng Chen, Hui-Yi Liao, Chien-Jen Wang, Jhih-Sheng Chen, Hui-Ling
Lee*, Biomarkers., 2016, 24, 1-7. (通訊作者, SCI, impact factor: 2.016, Ranking (Toxicology): 58/89 = 65.2 % ,
5-Year IF: 2.120). Times cited: 0. 25.
“Disturbances to neurotransmitter levels
and their metabolic enzyme activity in a freshwater planarian exposed to
cadmium” Jui-Pin Wu, Mei-Hui Li, Jhih-Sheng Chen, Szu-Yao Chung, Hui-Ling
Lee*, NeuroToxicology., 2015, 47, 72-81(通訊作者, SCI, impact factor: 3.054,
Ranking (Toxicology): 26/87 = 29.8 % , 5-Year IF: 3.291). Times cited: 0. 26.
“Fast and
simple screening for the simultaneous analysis of seven metabolites derived
from five volatile organic compounds in human urine using on-line solid-phase
extraction coupled with liquid chromatography-tandem mass spectrometry”
Wen-Chieh Chiang, Chao-Yu Chen, Ting-Chen Lee, Hui-Ling Lee*, Yu-Wen Lin.
Talanta., 2015, 132, 469-478. (通訊作者, SCI, impact factor: 3.511,
Ranking (Chemistry, Analytical): 12/76 = 15.79 %, 5-Year IF: 3.756). Times
cited: 0. 27.
“Identification
of trans , trans -2,4-Decadienal metabolites in mouse and human cells using
liquid chromatography - mass spectrometry” , Kao-Lu Pan, Wei-Jan Huang,
Ming-Hua Hsu, Hui-Ling Lee, Huei-Ju Liu, Chia-Wei Cheng, Ming-Hsien Tsai,
Mei-Ya Shen, and Pinpin Lin*. Chem. Res. Toxicol. (2014), 27, 1707-1719,
(SCI, impact factor: 4.19, Ranking (Toxicology): 12/87 = 13.79 %):, 5-Year
IF: 4.122 28.
“Cadmium
Neurotoxicity to a Freshwater Planarian” , Jui-Pin Wu, Hui-Ling Lee, Mei-Hui Li. Arch Environ Contam
Toxicol, (2014) 67, 639-650, DOI 10.1007/s00244-014-0056-0, (SCI, impact
factor: 1.96, Ranking (Environmental Science): 93/215 = 43.25 %, 5-Year IF:
2.135 29.
“Metabolomic
profiling of mice urine and serum associated with trans-trans 2, 4-decadienal
induced lung lesions by liquid chromatography-mass spectrometry”. Pinpin Lin,
Hui-Ling Lee*, Hao-I Cheng, Chao-Yu Chen, Ming-Hsien Tsai and Huei-Ju Liu.
Analytical and Bioanalytical Chemistry, (2014) 406, 17, 4287-4297, (SCI,
impact factor: 3.578, Ranking (Chemistry, Analytical): 11/76 = 14.47, 5-Year
IF: 3.744 30.
“Allostatic
load model associated with indoor environmental quality and sick building
syndrome among office workers”, Chien-Cheng Jung, Hsiu-Hao Liang, Hui-Ling
Lee, Nai-Yun Hsu, Huey-Jen Su, PLOS ONE (2014), 9, April 2014. 5-Year IF:
4.24. 31. "Six-month follow-up study of
health markers of nanomaterials among workers handling engineered nanomaterials"
Hui-Yi Liao, Yu-Teh Chung, Ching-Huang Lai, Shu-Li Wang, Hung-Che Chiang,
Lih-Ann Li, Tsui-Chun Tsou, Wan-Fen Li, Hui-Ling Lee, Wei-Te Wu, Ming-Hsiu
Lin, Jin-Huei Hsu, Jiune-Jye Ho, Chiou-Jong Chen, Tung-Sheng Shih, Chin-Chi
Lin, Saou-Hsing Liou, Nanotoxicology, December 2013, 1-11 (SCI) (notation：DOI: 10.3109/17435390.2013.858793,
Nanotoxicology : 1–11. 2012 Impact Factor: 7.844 ) 32. “Positive association between
urinary levels of 8-hydroxydeoxyguanosine and the acrylamide metabolite
N-acetyl-S-(propionamide)-cysteine in adolescents and young adults” Chien-Yu
Lin, Hui-Ling Lee, Yu-Chuan Chen,
Guang-Wen Lien, Lain-Yu Line, Journal of Hazardous Materials, 2013, 261, 372–
377. (SCI, impact factor: 3.925, Ranking (Environmental Science): 16/210 =
0.07 %, 5-Year IF: 4.679). T 33. “4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
(NNK) metabolism-related enzymes gene polymorphisms, NNK metabolites levels
and urothelial carcinoma”, Chi-Jung Chung, Yeong-Shiau Pu, Horng-Sheng Shiue,
Hui-Ling Lee, Pinpin Lin Hsiu-Yuan
Yang, Chien-Tien Su, Yu-Mei Hsueh, Toxicology Letters, 2013, 216, 16– 22.
(SCI, impact factor: 3.230, Ranking (Toxicology): 19/83 = 22.9 %, 5-Year IF:
3.557). 34. ”Joint effect of arsenic
methylation profile and NNK metabolites on urothelial carcinoma”, Chia-Chang
Wu, Chien-Tien Su, Hui-Ling Lee,
Chi-Jung Chung, Chao-Yuan Huang, Yeong-Shiau Pu, Pinpin Lin and Yu-Mei Hsueh，The
Journal of Urology, 2012,
188, 1701-1705 (SCI) 5 years IF: 4.02 35. ”Enhancement between environmental
tobacco smoke and arsenic on emphysema-like lesions in mice”, Chien-Kai Wang, Hui-Ling Lee, Han Chang, Ming-Hsien
Tsai, Yu-Chun Kuo and Pinpin Lin*, Journal of
Hazardous Materials,
2012, 221-222, 256-263. (SCI), 5 years IF: 3.997 36. ”Epidemiological study of health
hazards among workers handling engineered nanomaterials”, Saou-Hsing Liou,
Tsui-Chun Tsou, Shu-Li Wang, Lih-Ann Li, Hung-Che Chiang, Wen-Fen Li, Pin-Pin
Lin, Ching-Huang Lai, Hui-Ling Lee,
Jin-Hue Hsu, Chiou-Rong Chen, Tung-Sheng Shih, Hui-Yi Liao and Yu-Teh Chung， Journal of
Nanoparticle Research,
2012, 14, 878-893 (SCI), 5 years IF: 3.287 37. ”In vivo and in vitro metabolism
of tobacco-specific nitrosamine,
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK),by the freshwater
planarian, Dugesia japonica”, Jui-Pin Wu,
Mei-Hui Li, Jhih-Sheng Chen and Hui‑Ling Lee*, Chemosphere, 2012, 87, 1341-1347. (通訊作者, SCI, impact factor: 3.155,
Ranking (Environmental Sciences): 28/193 = 14.5%. (SCI),
5-Year IF: 3.559) 38. “Carcinogenic potencies
of polycyclic aromatic hydrocarbons for back-door neighbors of restaurants
with cooking emissions”, Jein-Wen
Chen, Shu-Li Wang, Dannis Paul Hsientang Hsieh,
His-Hsien Yang, and Hui‑Ling Lee*,
Science of the Total Environment, 2012, 417-418, 68-75. (通訊作者, SCI, impact factor: 3.19, Ranking (Environmental
Sciences): 26/193 = 13.5%. 39.
“4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
is correlated with 8-hydroxy-2'--deoxyguanosine in humans after exposure to environmental
tobacco smoke”, Hung-Che Chiang , Yung-Kai Huang, Pei-Fen Chen , Chia-Chi
Chang , Chien-Jen Wang,
Pinpin Lin* and Hui-Ling
Lee * , Science
of the Total Environment, 2012, 414, 134-139. (通訊作者, SCI, impact factor: 3.19, Ranking (Environmental
Sciences): 26/193 = 13.5%. 40. “Rapid and simple one-step
membrane extraction for the determination of 8-hydroxy 41.
“Metabolic effects of CYP 42.
Low ratio
of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol-glucuronides
(NNAL-Gluc)/free NNAL increases urothelial carcinoma risk”, Chi-Jung Chung, Hui-Ling
Lee, Hsiu-Yuan Yang,
Pinpin Lin, Yeong-Shiau Pu, Horng-Sheng Shiue, Chien-Tien Su, Yu-Mei Hsueh, Science of the Total Environment, 409, 1638-1642, 2011. (SCI impact
factor: 3.19, Ranking (Environmental
Sciences): 26/193 = 13.5%). 43. Hui-Ling Lee, Dennis P. H. Hsieh, Lih-Ann Li, (2010)
“ Polycyclic aromatic
hydrocarbons in cigarette sidestream smoke particulates from a Taiwanese
brand and their carcinogenic relevance” Chemosphere, 82, 477-482, 2011. (第一作者SCI impact factor:
3.155, Ranking (Environmental
Sciences): 28/193 = 14.5%) 44. Chien-Jen Wang , Ning-Hsiang Yang, Saou-Hsing Liou ,Hui-Ling Lee *, (2010)“
Fast quantification of the exhaled breath condensate of oxidative stress
8-iso-prostaglandin F2α using on-line solid-phase extraction coupled with
liquid chromatography/electrospray ionization mass spectrometry” Talanta.,
82, 1434-1438 (SCI), impact factor 3.206. 45. Hsien-Yu Cheng, Show-Chuen Chen*, Hui-Ling
Lee* (2010) “Fast analysis of phenolic acids by microchip
capillary electrophoresis with serpentine channel and end wrapped electrode”
J. Chin. Chem. Soc., 57, 371-377 (SCI), impact factor
0.77 46. Shun-ChiehYoung,
LouisW.Chang, Hui-Ling Lee, Lung-Hung Tsai, Yin-Chang Liu, and
Pinpin Lin* (2010)
“ DNA damage induced by trans, trans-2,4-decadienal (tt-DDE), a component of cooking
oil fume, in human bronchial epithelial cells” Environmental
and Molecular Mutagenesis, 51, 315-321. (SCI), impact factor
2.181. 47. Hui-Ling Lee, Yu-Mei Hsueh, Chi-Jung Chung, Louis W. Chang, Dennis Paul
Hsientang Hsieh, Pinpin Lin “Correlation between
urinary NNK metabolites, metabolic index and DNA adducts in a human
population” Cancer Epidemiology, Biomarker & Prevention, 17,
(2008) 3390-3395. (SCI), impact factor 4.642 48. Hui-Ling Lee, Louis W. Chang, Jui-Pin Wu, Yune-Fang
Ueng, Ming-Hsien Tsai, Dennis Paul Hsientang. Hsieh, Pinpin Lin,
“Enhancements of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
metabolism and carcinogenic risk via NNK/Arsenic interaction” Toxicology
Applied and Pharmacology, 227, (2008) 108-114. (SCI), impact
factor 4.72. 49. Hui-Ling Lee, Chiying Wang, Susana Lin, Dennis
Paul Hsientang Hsieh, “Liquid chromatography/tandem mass spectrometric method
for the simultaneous determination of tobacco-specific nitrosamine NNK and
its five metabolites” Talanta, 73 (2007) 76-80. (SCI), impact
factor 2.81 50. Hsi-Hsien Yang, Shu-Mei Chien, Hui-Ling Lee, Mu-Rong Chao, Hong-Wei Luo, Hsien-Tang
Hsieh, Wen-Jhy Lee, “Emission of trans,trans-2,4-decadienal
from restaurant discharges to the atmosphere” Atmospheric Environment, 41 (2007)
5327-5332. (SCI), impact
factor 2.63 51. Hui-Ling Lee, Show-Chuen Chen, “Microchip capillary
electrophoresis with amperometric detection for several carbohydrates” Talanta,
64 (2004) 210-216. (SCI), impact factor 2.532 52. Hui-Ling Lee, Show-Chuen Chen, “Microchip
capillary electrophoresis with electrochemical detector for precolumn
enzymatic analysis of glucose, creatinine, uric acid and ascorbic acid in
urine and serum” Talanta, 64 (2004) 750-757. (SCI), impact factor
2.532 |
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