周善行   教授

描述: 描述: 描述: 描述: Shang-Shing P

通訊處

辦公室電話︰(02)2905-2474

實驗室電話：(02)2905-3583

E-mail

chem1004@mails.fju.edu.tw

網頁連結

 

學經歷

輔仁大學化學系學士(1971)
美國University of Michigan 博士(1979)
美國University of Texas at Austin 博士後副研究員(1979–1980)
輔仁大學化學系副教授(1980–1984) ；教授(1984–)
輔仁大學化學系主任(1986–1990) ；理工學院院長(1990–1996)總務長(1996–2000) ；全人教育中心主任(2000–2002)；行政副校長(2002-2003)；進修部主任(2008-)

輔仁大學傑出學術研究成果獎(1988、1993、1996、1999、2003)；國科會優等研究獎(1989–1992) ；甲等獎(1980–); 中國化學會會誌論文獎(1989)教育部教學特優獎(1992)；台北縣優良教師(1997)：輔仁大學教師教學績優獎(2001,2003);私立教育事業協會模範教師獎(2001)

學術專長

有機化學及材料化學

研究領域

本實驗室研究的範圍主要是在有機合成，研究新的合成方法及其應用。特別有興趣在含硫取代之化合物，例如丁二烯石風衍生物與含硫之有機金屬之合成與應用，含硫之雜環化合物在非線性光學材料與藥物化學之研究。另外也對於有機電激發光材料之合成與應用，以及核酸切割劑治療腫瘤之研究有興趣。

代表著作

1.     Yih-Fong Liew, Chao-Tzu Huang, Shang-Shing P. Chou, Yuh-Chi Kuo,

 Shiu-Huey Chou, Jyh-Yih Leu, Woan-Fang Tzeng, Su-Jane Wang, Ming-Chi

   Tang and Rwei-Fen Syu Huang,* 2010, The Isolated and Combined Effects of

 Folic Acid and Synthetic Bioactive Compounds against Aβ(25-35)-Induced

 Toxicity in Human Microglial Cells, Molecules, 15, 1632-1644. (SCI) IF 1.974

2.  Shang-Shing P. Chou* and Chih-Fen Liu, 2010, A Rapid, Solvent-Free

   Phase-Transfer Catalysis for N-Alkylation of Dihydropyridones and Construction

   of the Indolizidine, Quinolizidine and Pyridoazepeine Structures, J. Chin. Chem.

   Soc. 57, 811-819. (SCI) IF 0.644

3.  Shang-Shing P. Chou* and Yi-Lin Cai, 2011, Synthesis and Applications of

   Sulfur-Substituted cis-Hexahydro-2-quinolinones, Tetrahedron, 67, 1183-1186.

   (SCI) IF 2.983

4.  Tzu-Yu Lin, Cheng-Wei Lu, Shu-Kuei Huang, Shang-Shing P. Chou, Yuh-Chi

 Kuo, Shiu-Huey Chou, Woan-Fang Tzeng, Chieh-Yih Leu, Rwei-Fen S. Huang,

 Yih-Fong Liew, Su-Jane Wang,* 2011, HTDP-2, a New Synthetic Compound,

 Inhibits Glutamate Release through Reduction of Voltage-Dependent Ca 2+ Influx

 in Rat Cerebral Cortex Nerve Terminals, Pharmacology, 88, 1-2, 26-32. (SCI) IF

 1.603

5.  Shang-Shing P. Chou,* Yi-Ching Chung, Po-An Chen, Shan-Lun Chiang, and

   Chien-Jung Wu, 2011, Synthetic Applications of Sulfur-Substituted Indolizidines

 and Quinolizidines, J. Org. Chem. 76, 692-695. (SCI) IF 3.818

6.  Shang-Shing P. Chou,* Tsung-Han Yang, Wan-Shiuan Wu, and Tzu-Han Chiu,

 2011, Stereospecific Synthesis of trans-5,6-Dihydropyridinones, Synthesis,

 759-763. (SCI) IF 2.184

7.  Shang-Shing P. Chou,* Chien-Wen Huang, and Chih-Chun Chang, 2011,

 Synthesis and Cycloaddition Reactions of Sulfur-Substituted Quinolizidine Dienes, Tetrahedron, 67, 4505-4513. (SCI) IF 2.983

8.  Shang-Shing P. Chou,* Bing-Heng Lee, Cheng-Han Ni, Yu-Chou Lin, 2011,

 Synthesis and Reactions of sulfur-Substituted Indolizidinones, Tetrahedron, 67,

 5395-5401. (SCI) IF 2.983

9.  Shang-Shing P. Chou,* and Chien-Jhung J. Wu, 2012, Ring Opening of

 Dihydro-2-pyridones and Intramolecular Diels－Alder Reactions, Tetrahedron,

 68, 1185-1191. (SCI) IF 3.060

10. Shang-Shing P. Chou,* Chang-Lin Lu and Yen-Hao Hsu, 2012, Synthesis of

 Triazolyl-Substituted Quinolizidine Imides, J. Chin. Chem. Soc. 59, 365-372. (SCI) IF 0.644

11. Shang-Shing P. Chou,* Jui-Chi Juan, Shwu-Chen Tsay, Kuei Pin Huang and Jih Ru

   Hwu,* 2012, Oxime Esters of 2,6-Diazaanthracene-9,10-dione and

   4,5-Diazafluoren-9-one as Photo-induced DNA-Cleaving Agents, Molecules, 17,

   3370-3382. (SCI) IF 2.411

12. Shang-Shing P. Chou,* and Chien-Jhung J. Wu, 2012, Chiral Synthesis of

 Indolizidines 209D and 167B via Asymmetric Oxidation of Sulfides and

 Sulfoxides, Tetrahedron, 68, 5025-5030. (SCI) IF 3.060

13. Shang-Shing P. Chou,* Jhih-Liang Huang, 2012, Tandem cross metathesis and

 intramolecular aza-Michael reaction to synthesize bicyclic piperidines and

 indolizidine 167E, Tetrahedron Lett. 53, 5552-5554. (SCI) IF2.588

14. Shang-Shing P. Chou,* Shan-Lun Chiang, Guan-Lin Huang, Bi-Shan Chiang,

 Ya-Chien Yu, 2013, New Synthesis and Reactions of Indolizidine 167E and

 Indolizidine Derivatives, Tetrahedron, 69, 274-283. (SCI) IF 3.060

15. Shang-Shing P. Chou,* Jun-Wei Zhang, Kuan-Hua Chen, 2013, Synthetic Studies

 of Quinolizidine 195C and Derivatives, Tetrahedron, 69, 1499-1508. (SCI) IF

 3.060

16. Shang-Shing P. Chou* and Jhih-Liang Huang, 2013, Studies toward the First

 Stereoselective Total Synthesis of (±)-Quinolizidine 195C and Other

 Transformations, Molecules, 18, 8243-8256. (SCI) IF 2.679

17. Shang-Shing P. Chou* and Chao-Hsiang Kao, 2013, Synthetic Transformations of

 Sulfur-Substituted 4-Quinolizidinones, J. Chin. Chem. Soc. 60, 1260-1266. (SCI)

 IF 0.879

18. Jih Ru Hwu,* Shwu-Chen Tsay, Shih Chin Hong, Ming-Hua Hsu, Chih-Fen Liu,

and Shang-Shing P. Chou*, 2013, Relationship Between Structure of Conjugated

Oxime Esters and Their Ability to Cleave DNA, Bioconjugate Chem. 24,

1778−1783. (SCI) IF 4.580

19. Jung-Sen Liu, Fang Jung, Shih-Hsing Yang, Shang-Shing P. Chou, Jhih-Liang

 Huang, Chang-Lin Lu, Guan-Lin Huang, Pan-Chyr Yang, Jau-Chen Lin*,

 Guey-Mei Jow*, 2013, FJU-C4, a New 2-Pyridone Compound, Attenuates

 Lipopolysaccharide-Induced Systemic Inflammation via p38MAPK and NF-kB in

 Mice, Plos one, 8, e82877. (SCI) IF 3.730

20. Shang-Shing P. Chou,* Kuo-Shiun Yang, and Tzu-Han Chiu, 2014, Synthesis of

 the Precursors of Pumiliotoxin 251D and Awajanomycin and Related Studies,

 Heterocycles, 89, 679-691. (SCI) IF 1.077

21. Shang-Shing P. Chou* and Wan-Shiuan Wu, 2014, Synthesis and reactions of

 sulfur-substituted α,β-unsaturated δ- and γ-lactones, Tetrahedron, 70,

 1847-1854. (SCI) IF 3.060